Pius II suna ne da wani limamin cocin Katolika ya ɗauka. Sunan haihuwarsa Enea Silvio Piccolomini kuma ya yi aiki a matsayin Paparoma daga 1458 zuwa 1464. Sunan "Pius" yana nufin "mai tsoron Allah" ko "mai ibada" a cikin harshen Latin, kuma ya kasance sanannen suna ga Paparoma a tsawon tarihi. Don haka, "Pius II" gabaɗaya yana nufin Enea Silvio Piccolomini a lokacin sarautarsa.
